Epstein-Barr Virus (EBV) drives cancer by inducing DNA breakage and genome instability
Biologists identified the mechanistic link between EBV and cancer. They discovered that the protein EBNA1 encoded by EBV binds to specific sequences on chromosome 11 of humans. This binding triggers chromosome breakage and genome instability. Genome instability is a known driver of cancer development.
April 18, 2023